{"id":4981,"date":"2025-02-13T01:07:57","date_gmt":"2025-02-13T01:07:57","guid":{"rendered":"https:\/\/airna.docksal.site\/therapeutic-areas\/"},"modified":"2026-04-07T11:13:57","modified_gmt":"2026-04-07T11:13:57","slug":"pipeline","status":"publish","type":"page","link":"https:\/\/airna.com\/de\/pipeline\/","title":{"rendered":"Pipeline"},"content":{"rendered":"\n\t
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Pipeline<\/h2>\n\n\n\n
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Unsere breit angelegte Pipeline zielt darauf ab, krankheitsverursachende genetische Varianten zu reparieren oder eine bessere Gesundheit durch die Einf\u00fchrung vorteilhafter RNA-Formen zu erm\u00f6glichen. <\/strong><\/h3>\n<\/div>\n\n\n\n
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EIN PR\u00c4ZISIONSANSATZ F\u00dcR AATD<\/h2>\n\n\n\n
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Unsere Therapeutika sollen Patienten erstklassige L\u00f6sungen bieten. <\/strong><\/h3>\n<\/div>\n\n\n\n
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Alpha-1-Antitrypsin-Defizit (AATD) ist eine vererbte Krankheit, die durch unzureichende Mengen des funktionellen Alpha-1-Antitrypsin-Proteins (AAT) aufgrund einer seltenen, sch\u00e4dlichen genetischen Variante verursacht wird. Dieses Defizit kann zu schweren Lungen- und Lebererkrankungen f\u00fchren, f\u00fcr die keine ausreichenden Behandlungsoptionen vorliegen. <\/p>\n\n\n\n

AATD eignet sich besonders gut f\u00fcr das RNA-Editing. Unser Hauptprogramm AIR-001 zielt darauf ab, eine funktionelle Heilung f\u00fcr Patienten zu erm\u00f6glichen, indem die krankheitsausl\u00f6sende genetische Variante, die der Erkrankung zugrunde liegt, repariert wird. AIR-001 ist darauf ausgelegt, diese Ver\u00e4nderung genau r\u00fcckg\u00e4ngig zu machen und die funktionelle AAT-Proteinproduktion wiederherzustellen. <\/p>\n\n\n\n

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Erfahren Sie mehr \u00fcber AATD und pr\u00e4zises RNA-Editing<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\n\t<\/div>\n<\/div><\/div>\n\n\n\n
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Gesundheitswandel durch pr\u00e4zises RNA-Editing<\/h2>\n\n\n\n
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Wir wollen das volle Potenzial des RNA-Editing aussch\u00f6pfen um die Gesundheit der Menschen zu verbessern.<\/strong><\/h3>\n<\/div>\n\n\n\n
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Dank der Fortschritte in der Genomik konnten sch\u00e4dliche genetische Varianten identifiziert werden, die das Krankheitsrisiko einer Person erh\u00f6hen, sowie n\u00fctzliche Varianten, die zu ges\u00fcnderen Ergebnissen f\u00fchren, z. B. zur Vermeidung von erh\u00f6htem Cholesterinspiegel. <\/p>\n\n\n\n

Der RNA-Editing-Ansatz von AIRNA hat ein einzigartiges Potenzial f\u00fcr die Entwicklung von Medikamenten, die entweder sch\u00e4dliche Varianten reparieren oder n\u00fctzliche Varianten einf\u00fchren, um die Gesundheit breiter Bev\u00f6lkerungsgruppen zu verbessern. Unsere Therapeutika sind so konzipiert, dass sie durch eine praktische und sichere Dosierung verabreicht und bei Bedarf abgesetzt werden k\u00f6nnen.<\/p>\n<\/div>\n<\/div>\n\n<\/div>\n\n\t<\/div>\n\n

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Seltene genetische Erkrankungen<\/h2>\n\n
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H\u00e4ufige Erkrankungen<\/h2>\n\n
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Erfahren Sie, wie kleine Ver\u00e4nderungen der RNA gro\u00dfe Auswirkungen auf die Krankheitsbehandlung haben k\u00f6nnten<\/strong><\/p>\n\n\n\n

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Wissenschaft und Plattform<\/a><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Seltene genetische Erkrankungen H\u00e4ufige Erkrankungen Erfahren Sie, wie kleine Ver\u00e4nderungen der RNA gro\u00dfe Auswirkungen auf die Krankheitsbehandlung haben k\u00f6nnten<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-4981","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPipeline — Airna<\/title>\n<meta name=\"description\" content=\"Pipeline Unsere breit angelegte Pipeline zielt darauf ab, krankheitsverursachende genetische Varianten zu reparieren oder eine bessere Gesundheit durch\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/airna.com\/de\/pipeline\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta 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